TIMI IIB compared the effects of an invasive vs. conservative strategy following thrombolysis with rtPA among patients with ST elevation myocardial infarction, and the effect of immediate vs. delayed (6 days) metoprolol therapy among patients with ST elevation myocardial infarction treated with rtPA (a substudy of the TIMI II trial).
MAIN RESULTS:
Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) phase II trial.

N Engl J Med. 1989 Mar 9;320(10):618-27.
PRESENTATIONS
OTHER PUBLICATIONS
Time as an Adjunctive Agent to Thrombolytic Therapy. J Thromb Thrombolysis. 1994;1(1):27-34.