Critical Care Cardiology Trials Network (CCCTN)

Progressive changes in cardiac critical care have driven a need for innovation in research and clinical care. The Critical Care Cardiology Trials Network (CCCTN) is a collaborative research network drawn from national leaders in critical care cardiology and coordinated by the TIMI Study Group.  Our mission is to design and execute observational studies and clinical trials that will advance the care of patients who require cardiac critical care.

Learn about the CCCTN COVID-PACT clinical trial, a multicenter, randomized, open-label, 2 x 2 factorial design trial of full-dose anticoagulation vs. standard-dose prophylactic anticoagulation and antiplatelet therapy vs. no antiplatelet therapy on the risk of venous or arterial thrombotic events in ICU patients with COVID-19. Study patients will be followed until their 28th day or hospital discharge, whichever comes first.

SLIDE SETS

CCCTN MCS Shock (Berg AHA 2019)

Temporary Mechanical Circulatory Support Use In Tertiary Cardiac Intensive Care Units Before And After The UNOS Heart Transplantation Allocation System Update: Insights From The Critical Care Cardiology Trials Network (CCCTN) Registry (Varshney ACC 2020)

PUBLICATIONS

Advanced Respiratory Support in the Contemporary Cardiac ICU

Incidence, underlying conditions, and outcomes of patients receiving acute renal replacement therapies in tertiary cardiac intensive care units: An analysis from the Critical Care Cardiology Trials Network Registry

Use of Temporary Mechanical Circulatory Support for Management of Cardiogenic Shock Before and After the United Network for Organ Sharing Donor Heart Allocation System Changes

Clinical Practice Patterns in Temporary Mechanical Circulatory Support for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry

Demographics, Care Patterns, and Outcomes of Patients Admitted to Cardiac Intensive Care Units: The Critical Care Cardiology Trials Network Prospective North American Multicenter Registry of Cardiac Critical Illness

Epidemiology of Shock in Contemporary Cardiac Intensive Care Units

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