Marc S. Sabatine, MD, MPH is Chairman of the Thrombolysis in Myocardial Infarction (TIMI) Study Group, the Lewis Dexter, MD, Endowed Chair in Cardiovascular Medicine at Brigham and Women’s Hospital (BWH), and a Professor of Medicine at Harvard Medical School (HMS).
Dr. Sabatine graduated magna cum laude from Harvard College and received his medical degree magna cum laude from HMS. He did his Internal Medicine residency, Chief Residency, and Cardiology clinical fellowship at the Massachusetts General Hospital (MGH). He received a Master of Public Health degree from the Harvard School of Public Health. Dr. Sabatine is board certified in Internal Medicine and Cardiology and attends in the coronary care units at both BWH & MGH. He is a Fellow of the American Heart Association, the American College of Cardiology, and the European Society of Cardiology.
As Chairman of the TIMI Study Group, Dr. Sabatine leads an Academic Research Organization whose mission over the past 40 years has been to advance the knowledge and care of patients suffering from cardiovascular disease and its risk factors. To that end, Dr. Sabatine has led multiple large-scale, international, randomized controlled trials of novel antithrombotic, lipid-lowering, and other pharmacotherapies. A pioneer in the multimarker approach to risk stratification, Dr. Sabatine has had several NIH and AHA grants supporting the application of proteomics and metabolomics for discovery of novel biomarkers. He has a long-standing interest in pharmacogenetics and has made seminal observations on the ability to use genetics for personalized medicine.
Dr. Sabatine has authored over 500 scientific articles including in the New England Journal of Medicine, JAMA, and the Lancet. He has given Cardiology or Medical Grand Rounds at top academic centers around the world and has authored numerous review articles and book chapters. He is the recipient of multiple honors and awards including the ACC Zipes Distinguished Young Scientist Award and has been inducted into the American Society of Clinical Investigation. He has been on the writing committees for several ACC/AHA and ESC practice guidelines. He is a Deputy Editor for JAMA Cardiology.
Polly Fish is the Director of Operations for the Thrombolysis in Myocardial Infarction (TIMI) Study Group at Brigham and Women’s Hospital (BWH). Ms. Fish oversees the development and execution of day-to-day operations, strategic planning, and innovative trial management solutions for sponsors and collaborators. Besides her previous business experience, Ms. Fish brings more than 20 years of cardiovascular clinical trial management experience to her position. Previously in her role as Senior Project Director at TIMI, she successfully led several of TIMI’s largest, international, randomized controlled trials including TRA 2˚P-TIMI 50, PEGASUS-TIMI 54 and DECLARE-TIMI 58.