Investigators

_MG_0978Christian T. Ruff, MD, MPH is an Associate Physician in the Cardiovascular Division at Brigham and Women’s Hospital and an Assistant Professor of Medicine at Harvard Medical School. Dr. Ruff graduated from Harvard University, earned his medical degree at Johns Hopkins University School of Medicine, and his masters of public health from the Harvard School of Public Health. Dr. Ruff completed his internal medicine residency and cardiovascular medicine fellowship at the Brigham and Women’s Hospital. Dr. Ruff is an investigator in the Thrombolysis in Myocardial Infarction (TIMI) Study Group and serves the Director of the Genetics Core Laboratory and the Co-Chairman of the Clinical Events Committee. He has led a broad array of projects, ranging from investigator initiated studies of biomarkers and genetic variants to large clinical trials. Dr. Ruff has investigated the efficacy of safety of antithrombotic therapies across the spectrum of cardiovascular disease, with a focus on stroke prevention in atrial fibrillation. Dr. Ruff has served on international antithrombotic guideline committees and has been invited to give hundreds of lectures nationally and internationally. He has authored many scholarly articles, editorials, reviews, and book chapters that include the New England Journal of Medicine, Lancet, Journal of the American Medical AssociationAmerican Journal of MedicineCirculation, Journal of the American College of Cardiology, and Nature Reviews Cardiology.

_MG_1333Erin Bohula May, MD, DPhil is an Associate Physician in Cardiovascular Medicine at Brigham and Women’s Hospital, an Instructor of Medicine at Harvard Medical School, and an Investigator at the TIMI Study Group. Dr. Bohula May earned her Doctor of Philosophy (D.Phil.) in Molecular Biology from Oxford University on a Rhodes Scholarship and her medical degree (M.D.) from Harvard Medical School. She completed her internal medicine residency and fellowships in cardiovascular medicine and critical care medicine at Brigham and Women’s Hospital. She is board certified in internal medicine, cardiology, and critical care medicine.

Dr. Bohula May’s research interests include the interplay of obesity, metabolic health and cardiovascular disease, evaluation of novel biomarkers and the application of innovative technologies for critically-ill cardiovascular patients. To this end, she is an investigator in a clinical trial studying the cardiovascular and metabolic impact of pharmacologic therapy for weight loss in obese or overweight individuals. In addition, she is investigating the prognostic utility of established and novel biomarkers for prediction of future cardiovascular events in multiple patient populations, including those with risk factors, stable vascular disease and acute coronary syndromes. Finally, she is studying novel, non-invasive methods of identifying and monitoring cardiogenic shock in the intensive care setting.

In addition to her scientific and trial responsibilities, Dr. Bohula May is an active member of the clinical staff at Brigham and Women’s hospital and attends in the Cardiology Critical Care Unit and inpatient General Cardiology Service.

Bergmark, BrianMD_12SQ (2)Brian Bergmark, MD is an Associate Physician in Interventional Cardiology in the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, an Instructor of Medicine at Harvard Medical School, and an Investigator at the TIMI Study Group. He received his BA from Stanford University and his MD from Harvard Medical School. Dr. Bergmark completed his residency in Internal Medicine, fellowship in Cardiovascular Medicine, and fellowship in Interventional Cardiology at the Brigham and Women’s Hospital. His research interests include acute coronary syndromes, cardiometabolic disease, and complex coronary interventions. In addition to his research work, Dr. Bergmark attends in the Cardiac Catheterization Laboratory.

MarstonDr. Nicholas Marston, MD, MPH is an Associate Physician in the Cardiovascular Division at Brigham and Women’s Hospital, an Instructor of Medicine at Harvard Medical School, and an Investigator at the TIMI Study Group. He graduated summa cum laude from the University of Texas at Austin, earned his medical degree from the University of Minnesota, and a master’s degree from Harvard School of Public Health. Dr. Marston completed his internship, residency, and chief medical residency in internal medicine at the University of California San Diego. He went on to complete his cardiovascular medicine fellowship at the Brigham and Women’s Hospital, where he served as chief cardiology fellow and received dedicated training in cardiovascular genetics and clinical trials. His research interests include novel lipid-lowering therapeutics, the genetics of cardiovascular disease, and translating genomic discovery into clinical practice. In addition to his research work, Dr. Marston attends in the Cardiovascular Genetics Center, where he cares for patients with familial hypercholesterolemia, premature coronary artery disease, and inherited cardiomyopathies and arrhythmias.

David Berg, MDDavid Berg, MD, MPH is an Associate Physician in Cardiovascular Medicine at Brigham and Women’s Hospital, an Instructor of Medicine at Harvard Medical School, and an Investigator in the TIMI Study Group. Dr. Berg graduated from Stanford University, earned his medical degree from Harvard Medical School, and earned his public health degree from Harvard T.H. Chan School of Public Health. Dr. Berg completed his internal medicine residency, chief residency, and dual fellowships in cardiovascular medicine and critical care medicine at Brigham and Women’s Hospital. He is an active member of the clinical staff at Brigham and Women’s Hospital, where he attends in the Levine Cardiac Intensive Care Unit. Dr. Berg’s research interests include cardiometabolic disease, heart failure, cardiogenic shock, and critical care cardiology. He is an investigator of several national and international clinical studies, including the DAPA ACT HF-TIMI 68 trial, the COVID-PACT trial, and the Critical Care Cardiology Trials Network (CCCTN) registry. Dr. Berg’s research also focuses on using circulating biomarkers to refine risk prediction, personalize treatment approaches, and characterize mechanisms of drug action.

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