ADVANCE MI-(TIMI 29) evaluated the efficacy and safety of facilitated PCI following the combination of reduced dose TNK-tpa and eptifibatide compared to primary PCI with eptifibatide alone in 148 patients with primary PCI for STEMI <6h. (Trial ended prematurely).
Facilitated percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: results from the prematurely terminated ADdressing the Value of facilitated ANgioplasty after Combination therapy or Eptifibatide monotherapy in acute Myocardial Infarction (ADVANCE MI) trial
Am Heart J. 2005 Jul;150(1):116-22.