HPS3/TIMI 55 REVEAL assessed the effect of cholesterol ester transfer protein (CETP) inhibition with anacetrapib 100 mg versus matching placebo on time to first major coronary event among 30,000 individuals with pre-existing vascular disease.
MAIN RESULTS:
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
N Engl J Med. 2017 Sep 28;377(13):1217-1227.
PRESENTATIONS
ESC 2017
Comparing Biomarker Profiles in Patients with Stable Atherosclerosis Treated with Anacetrapib versus Placebo: a Nested Proteomic Study from HPS3/TIMI 55-REVEAL (Berg, ESC 2019)
Biomarker-Based Heart Failure Risk Stratification in Patients with Atherosclerotic Cardiovascular Disease: Observations From HPS3 TIMI-55 REVEAL (Berg, AHA 2020)
OTHER PUBLICATIONS
Impact of ADCY9 Genotype on Response to Anacetrapib. Circulation. 2019 Jul 23;140(11):891-898.