PEGASUS – TIMI 54 was a randomized, double-blind, placebo-controlled trial to assess the prevention of thrombotic events with ticagrelor on a background of aspirin therapy in patients with history of myocardial infarction.
MAIN RESULTS:
Long-term use of ticagrelor in patients with prior myocardial infarction

N Engl J Med. 2015 May 7;372(19):1791-800.
PRESENTATIONS
Main Results (Sabatine, ACC 2015)
PEGASUS Renal dysfunction (ESC 15)
PEGASUS-TIMI 54 PCI Subgroup 2015
PEGASUS-TIMI 54 P2Y12 Inhibitor Withdrawal 2015
PEGASUS-TIMI 54 Diabetes Subgroup (Bhatt, ACC 2016)
PEGASUS-TIMI 54 PAD Subgroup 2016PEGASUS Total events (AHA)
Caffeine (Furtado, AHA 2018)
No PCI (Furtado, AHA 2018)
hsTn (Marston, AHA 2018)
PEGASUS TMAO (Gencer, AHA 2019)
A Novel Genetic Risk Score Predicts Ischemic Stroke in Patients with Cardiometabolic Disease (Patel, AHA 2020)
Clinical Applications of a Polygenic Risk Score to Predict Atrial Fibrillation in Patients with Cardiometabolic Disease (Garfinkel, AHA 2021)
A Genetic Risk Score to Predict Peripheral Artery Disease and Acute Limb Ischemia in Patients With Cardiometabolic Disease (Patel, AHA 2021)
Lipoprotein(a), Cardiovascular Events, and Benefit of P2Y12 Inhibition-Insights from the PEGASUS-TIMI 54 Trial (Patel, ESC 2022)
Development of a Novel Polygenic Risk Score to Predict Risk of Aortic Stenosis Events (Small, AHA 2022)