TIMI 10B compared the angiographic efficacy and safety of several doses of TNK with front loaded rtPA in 886 patients with Acute ST Elevation MI <12 hours.
MAIN RESULTS:
TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial
Circulation. 1998 Dec 22-29;98(25):2805-14.